WHY TAKE A CHANCE WITH ANYTHING ELSE?

 Aesculap's Gold Knee, with its patented seven-layer Advance Surface Technology, offers enhanced protection against the 
top prostheses-related reasons for 
implant failure and revision: metal ion release and wear.2

Metals such as nickel and cobalt chromium are widely used in artificial joints. Inside the body, 
all metals corrode, which can lead to the 
release of metal ions into surrounding tissue 
and the bloodstream. These metal ions can 
cause adverse reactions such as joint dysfunction 
or persistent pain in some patients, which can be 
a reason for implant failure and revision. Advanced Surface Technology features seven layers to act 
as a potential barrier to the release of metal ions.4,9

1 Klawitter JJ, Bagwell JG, Weinstein AM, Sauer BW. “An evaluation of bone growth into porous high density polyethylene.” J. Biomed Mater Reser. 1976 Mar;10(2):311-23.

2 Cheng BC, Koduri S, Wing CA, Woolery N, Cook DJ, Spiro RC. Porous titanium-coated polyetheretherketone implants exhibit an improved bone–implant interface: an in vitro and in vivo biochemical, biomechanical, and histological study. Medical Devices: Evidence and Research. 2018; Volume 11:391-402.

“Nano Features on a Titanium Interbody.” Aesculap Implant Systems, Whitepaper, 2017.



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more information!

THE SCIENCE BEHIND GOLD

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more 
information!

WHY GOLD?

Research on Aesculap's Advanced Surface Technology shows:

  • Superior surface hardness - two times harder than Oxinium and 
    eight times harder than traditional cobalt-chromium implants to resist abrasive wear.2-8

  • Significantly reduced wear.2,9,10 

  • Significantly reduced metal ion release.2,11 

1 Substances Added to 14th Report on Carcinogens. National Institute of Health. US Department of Health and Human Services. http://www.nih.gov/news-events/news-releases/seven-substances-added-14th-report-carcinogens. Assessed 1/23/17.
The results of in vitro testing have not been proven to quantitatively predict clinical performance with regard to implant wear or metal ion release. The absolute concentration that can trigger a hypersensitivity reaction to metal ions is unknown. A clinical evaluation of metal sensitivity was not performed with respect to Advanced Surface Technology.
3 AS Advanced Surface: ZrN: www.medthin.com. Coating Portfolio, 30.3.2011.
4 TiNbN and TiN: http://www.dot-coating.de/dotimplant source/beschichtung.html.
5 Biolox® Delta: Biolox Delta – Nanoverbundwerkstoff furr die Endoprothetik, Ceramtec® 07/10.
6 Oxinium®: Made for life Image brochure. S&N.
7 TiV: Zimmer® PM Newsletter 11/2006.
8 CoCr: Hardness of CoCrMo Implants. Aesculap data on file.
9 Luetzner, J. et al. (2015). SE12: Pre-Clinical Testing and Clinical Results of a Novel Coating for TKA Implant. This Scientific Exhibit is presented at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons in Las Vegas, NV, USA.
10 Data on File. Aesculap Test T018.
11 Reich, J. et al. (2010). Preclinical Evaluation of Coated Knee Implants for Allergic Patients. Der Orthopade, 39(5). Doi:10.1007/s11999-0099-1119-9.
12 Based on an extensive review of publicly available literature and promotional information accessed by 2/22/17. Metal polyethylene insert markers and metal patella marker are not available in Advanced Surface Technology.
13 Santana, A.E. et al. (2005) Relating Hardness-Curve Shapes with Deformation Mechanism in TiAIN Thin Films Enduring Indentation. Materials Science and Engineering A 406. 11-18.

IS THE GOLD KNEE RIGHT FOR YOU?

Metals such as nickel and cobalt chromium are widely used in artificial joints. Inside the body, all metals corrode, which can lead to the release of metal ions into surrounding tissue and the bloodstream. These metal ions can cause adverse reactions such as joint dysfunction or persistent pain in some patients, which can be a reason for implant failure and revision. Advanced Surface Technology features seven layers to act 
as a potential barrier to the release of 
metal ions.4,9

Metals such as nickel and cobalt chromium are widely used in artificial joints. Inside the body, 
all metals corrode, which can lead to the 
release of metal ions into surrounding tissue 
and the bloodstream. These metal ions can 
cause adverse reactions such as joint dysfunction 
or persistent pain in some patients, which can be 
a reason for implant failure and revision. Advanced Surface Technology features seven layers to act 
as a potential barrier to the release of metal ions.4,9

Metals such as nickel and cobalt chromium are widely used in artificial joints. Inside the body, 
all metals corrode, which can lead to the 
release of metal ions into surrounding tissue 
and the bloodstream. These metal ions can 
cause adverse reactions such as joint dysfunction 
or persistent pain in some patients, which can be 
a reason for implant failure and revision. Advanced Surface Technology features seven layers to act 
as a potential barrier to the release of metal ions.4,9

Give bone a solid grip.

Over 50,000 PlasmaporeXP spine devices implanted globally to date. Backed by 20 years of innovation in surface enhancements for spinal procedures and 30 years of experience with porous titanium surfaces.

Plasmapore®XP Surface Enhancing Technology

What is it?

A pure porous titanium osteoconductive surface applied to a PEEK-OPTIMA® core through a two-step, proprietary manufacturing process for the visualization advantages of PEEK with the mechanical strength of roughened titanium.

Download the Body of Evidence PDF here.

What are the benefits?

Offers ideal porosity necessary for bone growth to occur in stages fueled by the combination of macro, micro and nano features of the surface topography.1,2 You can find the full research paper here.

  • Increased migration resistance
  • Enhanced implant stability
  • Increased bone formation
  • Early bone apposition

Backed by our Integrity Warranty

Guarantees the strength of the titanium-to-PEEK interface and superior visualization properties. The confidence of the superiority of PlasmaporeXP Surface is reinforced by Aesculap’s unmatched experience.

Download the Integrity Warranty PDF here.

SEM analysis of PlasmaporeXP Surface Enhancement shows superimposed topographical features that are tens of nanometers in size.3

PlasmaporeXP Surface Enhancement has ideal porosity characteristics optimal for osteoconduction with porosity ranging from 35-60% and pore sizes from 60-150 microns.1

Surface features at the macro level are optimized for high initial stability and long-term migration resistance.

Nano

Micro

Macro

CT Scan

MRI

Give bone a 
solid grip. 

Plasmapore®XP Surface Enhancing Technology

Over 50,000 PlasmaporeXP spine devices implanted globally to date. Backed by 20 years of innovation in surface enhancements for spinal procedures and 30 years of experience with porous titanium surfaces.

Over 50,000 PlasmaporeXP spine devices implanted globally to date. Backed by 20 years of innovation in surface enhancements for spinal procedures and 30 years of experience with porous titanium surfaces.

What is it?

A pure porous titanium osteoconductive surface applied to a PEEK-OPTIMA® core through a two-step, proprietary manufacturing process for the visualization advantages of PEEK with the mechanical strength of roughened titanium.

Download the Body of Evidence PDF here.

MRI

What are the benefits?

Offers ideal porosity necessary for bone growth to occur in stages fueled by the combination of macro, micro and nano features of the surface topography.1,2 You can find the full research paper here. 

  • Increased migration resistance
  • Enhanced implant stability
  • Increased bone formation
  • Early bone apposition

Micro

Macro

Backed by our Integrity Warranty

Guarantees the strength of the titanium-to-PEEK interface and superior visualization properties. The confidence of the superiority of PlasmaporeXP Surface is reinforced by Aesculap’s unmatched experience.

Download the Integrity Warranty PDF here.